Steven Tyler and Sheryl Crow have both signed on to appear at the upcoming UNITE to Face Addiction Rally in Washington, D.C.

The event is set to take place on the National Mall on October 4 and they will be joined by a host of other top names including Joe Walsh, the Fray and Jason Isbell.

"UNITE to Face Addiction will mark the first time our nation will collectively stand up to addiction, a health problem that impacts one in three households," said Greg Williams, co-founder of Facing Addiction and a person in long-term recovery, in a statement.

"Twenty-two million Americans are currently suffering from a substance use disorder, and more than 23 million others are living in recovery."

He adds, "When you include the families of the afflicted, addiction impacts over 85 million people — we all know somebody.

It's not 'those' people, it's all of us."